The cees dekker Diaries

Nanotechnology gives A selection of prospects to add to biology. In this article I'll existing illustrations where nanofabrication – the ability to make confined structures with dimensions at will – is utilized to examine the biophysics of single molecules and cells. I will present some examples from our lab:

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I am able to barely think about how I, being a geneticist, would be capable to understand basic physics, let alone compete at the best. How did you go over it?

De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt over het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft met veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de

SMC complexes can go Actual physical roadblocks larger than their ring dimensions, indicating a nontopological mechanism for DNA loop extrusion

We use nanofabricated microfluidic buildings to sample spatial boundaries for microbes and biomimetic vesicles with reconstituted protein networks which evaluate the basic part of spatial confinement on the molecular and cellular level. Our projects include the following:

Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is shown in gray, the rim from the pore is highlighted in purple, along with a 3D rendering of your motion with the DNA rod is displayed.

‘Indeed, I comprehend persons were stunned at some time. At the end of the nineties, Once i was in my forties, I had been Professor of Molecular Electronics and I have to confess that it experienced ceesdekker.net become a bit bored, I didn’t study A lot anymore. The sphere went much more into the appliance facet, how you can integrate nanotubes into Digital circuits.

Right now, we also recognized that it should be achievable to utilize just one semiconducting carbon nanotube to help make a transistor — and we established out to make it. We stretched personal semiconducting nanotubes across metallic electrodes and used the fundamental silicon substrate for a gate electrode, developing The fundamental three-terminal structure of the discipline-impact transistor (Fig.

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Cees Dekker is Distinguished University Professor at TU Delft. Skilled being a physicist, he pioneered nanotechnology with a lot of discoveries on carbon nanotubes while in the nineties. Considering that 2000, he moved to solitary-molecule biophysics and nanobiology. His existing analysis focuses on (i) nanopores for protein sequencing; (ii) chromosome structure, especially SMC motor protein; and (iii) developing a residing synthetic cell from lifeless molecules. Dekker can be an elected member of the KNAW and fellow into the APS as well as IOP.

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 Last but not least, I'll briefly sketch several of our Strategies to take a look at the building of synthetic cells, particularly our very first measures to ascertain synthetic cell division.